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Setting a New Standard

INTESTI CURC™ (Cur-cure™) is the only curcumin product uniquely developed to relief Ulcerative Colitis symptoms*

The INTESTI CURC™ (Cur-cure™) Clinical Trial

Setting a New Standard

The results showed significantly better clinical and endoscopic improvement with INTESTI CURC™ compared with placebo.  Over half of the patients taking INTESTI CURC™ experienced clinical remission and over 65% experienced significant clinical improvement!  Moreover, 38% of the patients were in endoscopic remission at week 4, i.e. had no inflammation of the mucosal layer of the colon when examined by lower endoscopy. There were no significant side effects of INTESTI CURC™  in any of the patients.

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testimonials

What People Say About INTESTI CURC™

I was diagnosed with ulcerative colitis when I was in 8th grade.  I had terrible pain in my belly and anything from 5-10 bloody bowel movements per day.

The first medication I got was steroids and since then I’ve been on practically every drug conventional medicine had to offer me including biologics but nothing kept the inflammation down for long and I would have to be back on steroids eventually.

I started looking outside the conventional route for something that could help.  One of my doctors recommended that I try Cur-cure.  He said that it’s the only curcumin product that was clinically tested for ulcerative colitis.

I’m happy to say that for over a year now I’ve been clean of steroids and in complete clinical remission. Feeling better than ever!

Hana
Hana

I started taking Cur-cure after my doctor told me that I need to start taking medication that will suppress my immune system. After a week of taking Cur-cure I started to feel better, my abdominal pain and bleeding was reduced until they totally stopped!  My blood tests showed improvement in my condition.  After two months of Cur-cure treatment I had another colonoscopy and the results shocked my doctor. There was no trace of the inflammation!  My colon completely healed!  I was so happy that I was able to treat my intestinal inflammation naturally. I really recommend Cur-cure to anyone with digestive problems

Adi
Adi

I started taking Cur-cure 3 month ago.   I am not experiencing bleeding for over a month now, hurrah! So grateful, relieved and delighted about this! Also my bowel movements are very regular when I wake up in the morning which is revolutionary for me! Haha

Charlie
CharlieBotanist

More researches

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Berberine alone and in conjunction…

BERBERINE ALONE AND IN CONJUNCTION WITH IMMUNOMODULATORS DOWN-REGULATES PRO-INFLAMMATORY CD4+T-CELLS: IMPLICATIONS FOR…

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Curcumin, but not mesalamine

Curcumin, but not mesalamine

Curcumin, but not mesalamine, inhibits activated T-cells: Implications for combo curcumin-mesalamine UC therapy. Gastroenterology Unit, Sheba Medical Center…

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Curcumin add-on therapy…

Curcumin add-on therapy…

Curcumin add-on therapy for remission induction in mild-moderate active ulcerative colitis: A Multi-Center, Randomized, Placebo-Controlled Trial…

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The multi-center international clinical…

The multi-center international clinical…

The multi-center international clinical trial of CurCure™ food supplement for the treatment of patients with inflammation of the gut (a condition called ulcerative...

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FAQ

What makes INTESTI CURC™ special compared to other Curcumin products?

INTESTI CURC™ is the first Curcumin formulation that is specifically designed to treat gastro-intestinal disorders.  By combining traditional knowledge and modern scientific technology, Cur-cure™ is delivered directly to the mucosal layer of the intestines and induces its therapeutic properties straight at the target.

What is Curcumin?

Curcumin is a chemical compound found in the Indian spice turmeric. Tumeric has been used for thousands of years in Indian and Chinese traditional medicine to treat a wide range of medical problems from joint pain and snake bites to gastro-intestinal diseases.  Curcumin, the active ingredient responsible for these therapeutic advantages, has been isolated and researched extensively since the 1950s.  You should know that the spice turmeric contains between 2-4% active Curcumin.  INTESTI CURC™ contains 95% active Curcumin which basically means it is around 20 times as potent as the traditional remedy!

What is an “evidence-based food supplement”?

There are literally thousands of published scientific studies about Curcumin that have proven its many therapeutic properties.  Yet only a handful of these studies have been randomized, placebo-controlled trials, meaning the herbal food supplement is compared to sham (placebo) identical looking preparation, to know for sure that the herbal supplement is superior in its clinical efficacy. This design is the scientific and medical gold-standard for investigating a new medicinal.  In our view, food supplements should be supported by sufficient evidence and be evaluated by the same gold-standard if they are to be used to treat patients.    Only then they can be called “evidence-based food supplements”.

What is the evidence supporting INTESTI CURC™?

ITS Medical co-founders Prof. Shomron Ben-Horin and Nir Salomon are both leading experts in conventional and integrative medicine with extensive research and clinical experience. Realizing the current unmet medical need in the treatment of inflammatory bowel disease, they started in 2010 to research Curcumin with an aim to develop a product that would be specifically designed to treat intestinal inflammation.  They conducted in-vitro (laboratory) studies which showed Curcumin had a inhibitory effect on pro-inflammatory cells.  Knowing that many patients with inflammatory bowel disease are taking 5ASA drugs such as mesalamine, Nir Salomon and Prof. Ben-Horin further researched Curcumins interaction with these drugs and showed that they not only complemented each other’s anti-inflammatory actions but that Curcumin also possessed anti-inflammatory properties which melsamine did not.  The research results were presented at the World Gastroenterology Organization (WGO) conference in Shanghai in 2013.

This study set the stage for a clinical trial with INTESTI CURC™ in ulcerative colitis.  In order to critically test INTESTI CURC™, Prof Ben-Horin & Nir Salomon have designed with additional expert colleagues a randomized, placebo-controlled, double-blind study which was conducted in three different medical centers in Israel, Hong Kong and Cyprus.  The results of the study showed that Cur-cure™   was effective in inducing remission in patients with active ulcerative colitis who have failed treatment with conventional mesalamine.  Within four weeks alone Cur-cure™ induced clinical remission in over 60% of patients.  The study was published on the front cover of the prestigious medical journal Clinical Gastroenterology and Hepatology in August 2016 and was awarded YIA first prize in the IDDF conference in Hong Kong.  Read more about the researches with Cur-cure™ HERE (link to cur-cure research page)

How long to I have to take INTESTI CURC™ to see results?

Obviously this varies greatly from patient to patient.  Our study showed that patients with active ulcerative colitis experienced significant improvement after  4 weeks. Our clinical experience with INTESTI CURC™ is that first improvement in symptoms could be apparent even earlier.

Should I ask my physician about taking INTESTI CURC™?

Absolutely.  We strongly encourage that you inform your doctor about taking INTESTI CURC™ or if you are thinking of taking INTESTI CURC™.  You can download and print the clinical trial abstract from our website (link to research page which should have a download option) to give to your doctor. If needed, we are also always happy to be in contact with physicians in order to answer any questions.

What is the recommended dosage I should take?

Curcumin has been shown to be safe at very high doses (up to 12,000 mg a day!).   We found INTESTI CURC™ to be effective at much lower dosages and the dosage given in the clinical trial was 1 gram (two capsules of 500mg each) taken three times daily, for a total of 3gram of INTESTI CURC™ per day.  However, you should ask your physician about the recommended dose

Is INTESTI CURC™ effective for Irritable Bowel syndrome (IBS)?

In most IBS patients there is an active microscopic inflammatory process in the mucosal layer of the intestines.  Therefore, it’s not surprising that many IBS patients treated with INTESTI CURC™ report that it helped improve their symptoms and quality of life.  Having said that, although our clinical experience suggests INTESTI CURC™ is effective in treating IBS, we haven’t yet conducted a clinical trial in this field.

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